Luis Salazar Navarrete

Líneas de investigación

• Bases moleculares de enfermedades prioritarias
• Farmacogenómica

Proyectos adjudicados

• CISPLATIN-INDUCE NEPHROTOXICITY: CONTRIBUTION OF CLINICAL, GENETIC AND EPIGENETIC FACTORS (2020) Fuente: ANID-FAPESP | Rol:
• IDENTIFICACIÓN DE MECANISMOS EPIGENÉTICOS IMPLICADOS EN LA RENOPROTECCIÓN DE COMPUESTOS BIOACTIVOS FRENTE A LA NEFROTOXICIDAD INDUCIDA POR CISPLATINO. (2022) Fuente: CONICYT | Rol:

Tus publicaciones

• EFFECT OF STATINS ON LIPID METABOLISM-RELATED MICRORNA EXPRESSION IN HEPG2 CELLS Año: 2021 Link: https://doi.org/10.1007/s43440-021-00241-3
• CYPERUS SPP.: A REVIEW ON PHYTOCHEMICAL COMPOSITION BIOLOGICAL ACTIVITY AND HEALTH-PROMOTING EFFECTS Año: 2021 Link: https://doi.org/10.1155/2021/4014867
• EPIGENETIC MECHANISMS INVOLVED IN CISPLATIN-INDUCED NEPHROTOXICITY: AN UPDATE Año: 2021 Link: https://doi.org/10.3390/ph14060491
• PROTECTIVE EFFECT OF PINOT NOIR POMACE EXTRACT AGAINST THE CYTOTOXICITY INDUCED BY POLYCYCLIC AROMATIC HYDROCARBONS ON ENDOTHELIAL CELLS Año: 2020 Link: https://doi.org/10.1016/j.fct.2020.111947
• THERAPEUTIC POTENTIAL OF ISOFLAVONES WITH AN EMPHASIS ON DAIDZEIN Año: 2021 Link: https://doi.org/10.1155/2021/6331630
• DYSREGULATED MICRORNAS AS BIOMARKERS OR THERAPEUTIC TARGETS IN CISPLATIN-INDUCED NEPHROTOXICITY: A SYSTEMATIC REVIEW Año: 2021 Link: https://doi.org/10.3390/ijms222312765
• PRODIGIOSIN MODULATES THE IMMUNE RESPONSE AND COULD PROMOTE A STABLE ATHEROSCLEROTIC LESSION IN C57BL/6 LDLR-/- MICE Año: 2020 Link: https://doi.org/10.3390/ijms21176417
• DRIMENOL ISODRIMENINOL AND POLYGODIAL ISOLATED FROM DRIMYS WINTERI REDUCE MONOCYTE ADHESION TO STIMULATED HUMAN ENDOTHELIAL CELLS Año: 2020 Link: https://doi.org/10.1016/j.fct.2020.111775
• CONTROLLED RELEASE OF CAFFEIC ACID AND PINOCEMBRIN BY USE OF NPSI-CD COMPOSITES IMPROVES THEIR ANTIANGIOGENIC ACTIVITY Año: 2022 Link: https://doi.org/10.3390/pharmaceutics14030484
• AUTOPHAGY AND POLYPHENOLS IN OSTEOARTHRITIS: A FOCUS ON EPIGENETIC REGULATION Año: 2022 Link: https://doi.org/10.3390/ijms23010421
• DRIMYS WINTERI AND ISODRIMENINOL DECREASED FOAM CELL FORMATION IN THP-1 DERIVED MACROPHAGES Año: 2020 Link: https://doi.org/10.1016/j.fct.2020.111842
• HISTOLOGICAL EVALUATION AND GENE EXPRESSION PROFILING OF AUTOPHAGY-RELATED GENES FOR CARTILAGE OF YOUNG AND SENESCENT RATS Año: 2020 Link: https://doi.org/10.3390/ijms21228607
• ROLE OF MIRNAS AS BIOMARKERS OF COVID-19: A SCOPING REVIEW OF THE STATUS AND FUTURE DIRECTIONS FOR RESEARCH IN THIS FIELD Año: 2021 Link: https://doi.org/10.2217/bmm-2021-0348
• ATORVASTATIN INCREASES THE EXPRESSION OF LONG NON-CODING RNAS ARSR AND CHROME IN HYPERCHOLESTEROLEMIC PATIENTS: A PILOT STUDY Año: 2020 Link: https://doi.org/10.3390/ph13110382
• THE CURRENT STATE OF MICRORNAS AS RESTENOSIS BIOMARKERS Autores: Varela N.; Lanas F.; Salazar, L.A.; Zambrano T. Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=545256
• CHOLESTEROL-RELATED LNCRNAS AS RESPONSE PREDICTORS OF ATORVASTATIN TREATMENT IN CHILEAN HYPERCHOLESTEROLEMIC PATIENTS: A PILOT STUDY Autores: Isis Paez;Yalena Prado;Pía Loren;Carmen G. Ubilla;Nelia Rodríguez;Luis A. Salazar; Año: 2023 Link: https://doi.org/10.3390/biomedicines11030742
• RELATIONSHIP BETWEEN HYPOXIC AND IMMUNE PATHWAYS ACTIVATION IN THE PROGRESSION OF NEUROINFLAMMATION: ROLE OF HIF-1 AND TH17 CELLS Autores: Consuelo Arias;Paulina Sepúlveda;Rodrigo L. Castillo;Luis A. Salazar; Año: 2023 Link: https://doi.org/10.3390/ijms24043073
• CISPLATIN RESISTANCE: GENETIC AND EPIGENETIC FACTORS INVOLVED Autores: Yuliannis Lugones;Pía Loren;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/biom12101365
• MULTI-TARGET MECHANISMS OF PHYTOCHEMICALS IN ALZHEIMERS DISEASE: EFFECTS ON OXIDATIVE STRESS NEUROINFLAMMATION AND PROTEIN AGGREGATION Autores: Javad Sharifi-Rad;Simona Rapposelli;Simona Sestito;Jesús Herrera-Bravo;Alejandra Arancibia-Diaz;Luis A. Salazar;Balakyz Yeskaliyeva;Ahmet Beyatli;Gerardo Leyva-Gómez;Carlos González-Contreras;Eda Snmez Gürer;Miquel Martorell;Daniela Calina; Año: 2022 Link: https://doi.org/10.3390/jpm12091515
• MICRORNAS INVOLVED IN INTRINSIC APOPTOTIC PATHWAY DURING CISPLATIN-INDUCED NEPHROTOXICITY: POTENTIAL USE OF NATURAL PRODUCTS AGAINST DDP-INDUCED APOPTOSIS Autores: Pía Loren;Yuliannis Lugones;Nicolás Saavedra;Kathleen Saavedra;Isis Páez;Nelia Rodriguez;Patricia Moriel;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/biom12091206
• POLYCYCLIC AROMATIC HYDROCARBONS (PAHS) EXPOSURE TRIGGERS INFLAMMATION AND ENDOTHELIAL DYSFUNCTION IN BALB/C MICE: A PILOT STUDY Autores: Gabriel A. Rojas;Nicolás Saavedra;Kathleen Saavedra;Montserrat Hevia;Cristian Morales;Fernando Lanas;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/toxics10090497
• ANTHOCYANINS FOUND IN PINOT NOIR WASTE INDUCE TARGET GENES RELATED TO THE NRF2 SIGNALLING IN ENDOTHELIAL CELLS Autores: Jesús Herrera-Bravo;Jorge F. Beltrán;Nolberto Huard;Kathleen Saavedra;Nicolás Saavedra;Marysol Alvear;Fernando Lanas;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/antiox11071239
• STUDY OF THE MANDIBULAR BONE MICROSTRUCTURE AND BLOOD MINERALS BIOAVAILABILITY IN RAINBOW TROUT (ONCORHYNCHUS MYKISS WALBAUM 1792) FROM FRESHWATER Autores: Karina Godoy;Cristian Sandoval;Carlos Manterola-Barroso;Claudio Vásquez;Noelia Sepúlveda;Mariana Rojas;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/ani12121476
• MICRORNA-20A-5P DOWNREGULATION BY ATORVASTATIN: A POTENTIAL MECHANISM INVOLVED IN LIPID-LOWERING THERAPY Autores: Kathleen Saavedra;Karla Leal;Nicolás Saavedra;Yalena Prado;Isis Paez;Carmen G. Ubilla;Gabriel Rojas;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/ijms23095022
• LONG NON-CODING RNAS MIGHT REGULATE PHENOTYPIC SWITCH OF VASCULAR SMOOTH MUSCLE CELLS ACTING AS CERNA: IMPLICATIONS FOR IN-STENT RESTENOSIS Autores: Alberto Arencibia;Fernando Lanas;Luis A. Salazar; Año: 2022 Link: https://doi.org/10.3390/ijms23063074
• EFFECTS OF FOUR LIPID METABOLISM-RELATED POLYMORPHISMS ON BODY COMPOSITION IMPROVEMENTS AFTER 12 WEEKS OF HIGH-INTENSITY INTERVAL TRAINING AND DIETARY ENERGY RESTRICTION IN OVERWEIGHT/OBESE ADULT WOMEN: A PILOT STUDY Autores: Andrade-Mayorga; Omar; Diaz; Erik; Salazar; Luis A. Año: 2021 Link: https://doi.org/10.3389/fphys.2021.712787
• EPIGENETICS: A MISSING LINK BETWEEN EARLY LIFE STRESS AND DEPRESSION Autores: Saavedra; Kathleen; Salazar; Luis A.; Kim; YK Año: 2021 Link: https://doi.org/10.1007/978-981-33-6044-0_8
• ETHNOPHARMACOLOGY PHYTOCHEMISTRY AND BIOLOGICAL ACTIVITIES OF NATIVE CHILEAN PLANTS Autores: Salehi; Bahare; Sharifi-Rad; Javad; Herrera-Bravo; Jesus; Salazar; Luis A.; Delporte; Carla; Barra; Gabriela Valenzuela; Ramirez; Maria-Elena Cazar; Lopez; Maria Dolores; Ramirez-Alarcon; Karina; Cruz-Martins; Natalia; Martorell; Miquel Año: 2021 Link: https://doi.org/10.2174/1381612826666201124105623
• GENUS VIBURNUM: THERAPEUTIC POTENTIALITIES AND AGRO-FOOD-PHARMA APPLICATIONS Autores: Sharifi-Rad; Javad; Quispe; Cristina; Vergara; Cristian Valdes; Kitic; Dusanka; Kostic; Milica; Armstrong; Lorene; Shinwari; Zabta Khan; Khalil; Ali Talha; Brdar-Jokanovic; Milka; Ljevnaic-Masic; Branka; Varoni; Elena M.; Iriti; Marcello; Leyva-Gomez; Gerardo; Herrera-Bravo; Jesus; Salazar; Luis A.; Cho; William C. Año: 2021 Link: https://doi.org/10.1155/2021/3095514
• MICRORNA-33B IS A POTENTIAL NON-INVASIVE BIOMARKER FOR RESPONSE TO ATORVASTATIN TREATMENT IN CHILEAN SUBJECTS WITH HYPERCHOLESTEROLEMIA: A PILOT STUDY Autores: Ubilla; Carmen Gloria; Prado; Yalena; Angulo; Jeremy; Obreque; Ignacio; Paez; Isis; Saavedra; Nicolas; Saavedra; Kathleen; Zambrano; Tomas; Salazar; Luis A. Año: 2021 Link: https://doi.org/10.3389/fphar.2021.674252
• MICRORNAS HSA-MIR-618 AND HSA-MIR-297 MIGHT MODULATE THE PLEIOTROPIC EFFECTS EXERTED BY STATINS IN ENDOTHELIAL CELLS THROUGH THE INHIBITION OF ROCK2 KINASE: IN-SILICO APPROACH Autores: Leal; Karla; Saavedra; Kathleen; Rebolledo; Camilo; Salazar; Luis A. Año: 2021 Link: https://doi.org/10.3389/fcvm.2021.704175
• PHYSIOLOGICAL EFFECTS AND INTER-INDIVIDUAL VARIABILITY TO 12 WEEKS OF HIGH INTENSITY-INTERVAL TRAINING AND DIETARY ENERGY RESTRICTION IN OVERWEIGHT/OBESE ADULT WOMEN Autores: Andrade-Mayorga; Omar; Martinez-Maturana; Nicolas; Salazar; Luis A.; Diaz; Erik Año: 2021 Link: https://doi.org/10.3389/fphys.2021.713016
• SINGLE NUCLEOTIDE POLYMORPHISMS IN APOLIPOPROTEIN B APOLIPOPROTEIN E AND METHYLENETETRAHYDROFOLATE REDUCTASE ARE ASSOCIATED WITH SERUM LIPID LEVELS IN NORTHERN CHILEAN SUBJECTS. A PILOT STUDY Autores: Galvez; Anita S.; Ramirez; Hugo; Placencia; Pablo; Rojas; Claudio; Urzua; Ximena; Kalergis; Alexis M.; Salazar; Luis A.; Escobar-Vera; Jorge Año: 2021 Link: https://doi.org/10.3389/fgene.2021.640956
• THE THERAPEUTIC POTENTIAL OF WOGONIN OBSERVED IN PRECLINICAL STUDIES Autores: Sharifi-Rad; Javad; Herrera-Bravo; Jesus; Salazar; Luis A.; Shaheen; Shabnum; Abdulmajid Ayatollahi; Seyed; Kobarfard; Farzad; Imran; Muhammad; Imran; Ali; Custodio; Luisa; Dolores Lopez; Maria; Schoebitz; Mauricio; Martorell; Miquel; Kumar; Manoj; Ansar Rasul Suleria; Hafiz; Cho; William C. Año: 2021 Link: https://doi.org/10.1155/2021/9935451
• CIRCULATING MIRNA-23B AND MIRNA-143 ARE POTENTIAL BIOMARKERS FOR IN-STENT RESTENOSIS Autores: Saavedra; Nicolas; Rojas; Gabriel; Herrera; Jesus; Rebolledo; Camilo; Ruedlinger; Jenny; Bustos; Luis; Bobadilla; Braulio; Perez; Luis; Saavedra; Kathleen; Zambrano; Tomas; Lanas; Fernando; Salazar; Luis A. Año: 2020 Link: https://doi.org/10.1155/2020/2509039
• EFECTO ANTIANGIOGÉNICO DEL ÁCIDO CAFEICO Y PINOCEMBRINA EN EL PROCESO DE ANGIOGÉNESIS FISIOLÓGICA DE FETOS DE POLLO Autores: Patricia Olivares-O; María Paz Riquelme; Pedro Leiva-A; Luis A. Salazar; Dina Guzmán-Oyarzo; Carlos Rosas-C Año: 2020 Link: https://doi.org/10.4067/S0717-95022020000100135
• HIGH-INTENSITY INTERVAL TRAINING ON BODY COMPOSITION FUNCTIONAL CAPACITY AND BIOCHEMICAL MARKERS IN HEALTHY YOUNG VERSUS OLDER PEOPLE Autores: Nasri Marzuca-Nassr; Gabriel; Artigas-Arias; Macarena; Angelica Olea; Maria; SanMartin-Calisto; Yuri; Huard; Nolberto; Duran-Vejar; Fernanda; Beltran-Fuentes; Francisca; Munoz-Fernandez; Aris; Alegria-Molina; Andrea; Sapunar; Jorge; Salazar; Luis A. Año: 2020 Link: https://doi.org/10.1016/j.exger.2020.111096