Pamela Leal Rojas

Líneas de investigación

• Caracterización molecular de tumores tracto biliar
• Estudio de vesículas extracelulares como fuente de marcadores moleculares
• Evaluación de extractos naturales en modelos preclínicos

Proyectos adjudicados

• CONNECTING MOLECULAR SUBTYPES OF COLORECTAL CANCER WITH EXTRACELLULAR VESICLES HETEROGENEITY IN PATIENT-DERIVED ORGANOIDS (2021) Fuente: | Rol:
• ACCESSING UNTAPPED SOURCES OF NATURAL PRODUCTS: AN INNOVATIVE TRANSDISCIPLINARY MULTI-OMICS APPROACH FOR BIOACTIVE METABOLITES DISCOVERY IN ACTINOBACTERIA AND CYANOBACTERIA FROM EXTREME ENVIRONMENTS (2021) Fuente: | Rol:
• SETTING UP DE UNA PLATAFORMA DE PRODUCCIÓN DE ANTICUERPOS MONOCLONALES RECOMBINANTES, UTILIZANDO EL BIOMARCADOR CDLN18 DE CÁNCER DE VESÍCULA BILIAR (2021) Fuente: | Rol:

Tus publicaciones

• HIPPO-YAP1 IS A PROGNOSIS MARKER AND POTENTIALLY TARGETABLE PATHWAY IN ADVANCED GALLBLADDER CANCER Autores: García, Patricia; Rosa, Lorena; Vargas, Sergio; Weber, Helga; Espinoza, Jaime A.; Suárez, Felipe; Romero-Calvo, Isabel; Elgueta, Nicole; Rivera, Vanessa; Nervi, Bruno; Obreque, Javiera; Leal, Pamela; Viñuela, Eduardo; Aguayo, Gloria; Muñiz, Sabrina; Sagredo, Alfredo; Roa, Juan C.; Bizama, Carolina Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=530785
• THE ANTI-PROLIFERATIVE AND ANTI-INVASIVE EFFECT OF LEAF EXTRACTS OF BLUEBERRY PLANTS TREATED WITH METHYL JASMONATE ON HUMAN GASTRIC CANCER IN VITRO IS RELATED TO THEIR ANTIOXIDANT PROPERTIES Autores: Ribera-Fonseca, Alejandra; Jimenez, Danae; Leal, Pamela; Riquelme, Ismael; Carlos Roa, Juan; Alberdi, Miren; Peek, Richard M.; Reyes-Diaz, Marjorie Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=523054
• ANTHOCYANIN-RICH EXTRACTS OF CALAFATE (BERBERIS MICROPHYLLA G. FORST.) FRUITS DECREASE IN VITRO VIABILITY AND MIGRATION OF HUMAN GASTRIC AND GALLBLADDER CANCER CELL LINES Autores: Calderon-Reyes, Cristobal; Silva Pezoa, Ramon; Leal, Pamela; Ribera-Fonseca, Alejandra; Caceres, Cristina; Riquelme, Ismael; Zambrano, Tomas; Pena, Daniela; Alberdi, Miren; Reyes-Diaz, Marjorie Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=625122
• FUNCTIONAL AND GENOMIC CHARACTERIZATION OF THREE NOVEL CELL LINES DERIVED FROM A METASTATIC GALLBLADDER CANCER TUMOR Autores: Garcia, Patricia; Bizama, Carolina; Rosa, Lorena; Espinoza, Jaime A.; Weber, Helga; Cerda-Infante, Javier; Sanchez, Marianela; Montecinos, Viviana P.; Lorenzo-Bermejo, Justo; Boekstegers, Felix; Davila-Lopez, Marcela; Alfaro, Francisca; Leiva-Acevedo, Claudia; Parra, Zasha; Romero, Diego; Kato, Sumie; Leal, Pamela; Lagos, Marcela; Carlos Roa, Juan Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=578728
• CONTROLLED RELEASE OF CAFFEIC ACID AND PINOCEMBRIN BY USE OF NPSI-BETA CD COMPOSITES IMPROVES THEIR ANTIANGIOGENIC ACTIVITY Autores: Guzman-Oyarzo; Dina; Hernandez-Montelongo; Jacobo; Rosas; Carlos; Leal; Pamela; Weber; Helga; Alvear; Marysol; Salazar; Luis A. Año: 2022 Link: https://doi.org/10.3390/pharmaceutics14030484
• EXOSOMES AND CYSTIC ECHINOCOCCOSIS. SYSTEMATIC REVIEW Autores: Carlos Manterola; Pamela Leal Año: 2022
• CRISPR/CAS13-BASED PLATFORMS FOR A POTENTIAL NEXT-GENERATION DIAGNOSIS OF COLORECTAL CANCER THROUGH EXOSOMES MICRO-RNA DETECTION: A REVIEW Autores: Duran-Vinet; Benjamin; Araya-Castro; Karla; Calderon; Juan; Vergara; Luis; Weber; Helga; Retamales; Javier; Araya-Castro; Paulina; Leal-Rojas; Pamela Año: 2021 Link: https://doi.org/10.3390/cancers13184640