Felipe Simon Pino

Líneas de investigación

• Sepsis induced-organ dysfunction
• Vascular physiopathology during sepsis
• Inflammation induced-vascular disfunction
• Descubrimiento de marcadores para el tratamiento de sepsis.

Tus publicaciones

• ENDOTHELIAL DYSFUNCTION IN PREGNANCY METABOLIC DISORDERS Autores: Echeverria, C., Eltit, F., Santibanez, F., Gatica, S., Cabello-Verrugio, C., Simon, F., Año: 2020 Link: https://doi.org/10.1016/j.bbadis.2019.02.009
• TRPM7 MEDIATES KIDNEY INJURY, ENDOTHELIAL HYPERPERMEABILITY AND MORTALITY DURING ENDOTOXEMIA Autores: Gatica, S., Villegas, V., Vallejos, A., Olivares, P., Aballai, V., Lagos-Meza, F., Echeverria, C., Cabello-Verrugio, C., Varela, D., Simon, F., Año: 2020 Link: https://doi.org/10.1038/s41374-019-0304-z
• ANGIOTENSIN (1-7) DECREASES MYOSTATIN-INDUCED NF-KB SIGNALING AND SKELETAL MUSCLE ATROPHY Autores: Aravena, J., Abrigo, J., Gonzalez, F., Aguirre, F., Gonzalez, A., Simon, F., Cabello-verrugio, C., Año: 2020 Link: https://doi.org/10.3390/ijms21031167
• PROTECTIVE EFFECT OF ANGIOTENSIN 1-7 ON SARCOPENIA INDUCED BY CHRONIC LIVER DISEASE IN MICE Autores: Aguirre, F., Abrigo, J., Gonzalez, F., Gonzalez, A., Simon, F., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.3390/ijms21113891
• CHOLIC ACID AND DEOXYCHOLIC ACID INDUCE SKELETAL MUSCLE ATROPHY THROUGH A MECHANISM DEPENDENT ON TGR5 RECEPTOR Autores: Abrigo, J., Gonzalez, F., Aguirre, F., Tacchi, F., Gonzalez, A., Meza, P., Simon, F., Cabrera, D., Arrese, M., Karpen, S., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.1002/jcp.29839
• TRPV1-ESTRADIOL STEREOSPECIFIC RELATIONSHIP UNDERLIES CELL SURVIVAL IN OXIDATIVE CELL DEATH Autores: Ramírez-Barrantes, R., Carvajal-Zamorano, K., Rodriguez, B., Cordova, C., Lozano, C., Simon, F., Díaz, P., Muñoz, P., Marchant, I., Latorre, R., Castillo, K., Olivero, P., Año: 2020 Link: https://doi.org/10.3389/fphys.2020.00444
• SARCOPENIA INDUCED BY CHRONIC LIVER DISEASE IN MICE REQUIRES THE EXPRESSION OF THE BILE ACIDS MEMBRANE RECEPTOR TGR5 Autores: Abrigo, J., Campos, F., Gonzalez, F., Aguirre, F., Gonzalez, A., Huerta-Salgado, C., Conejeros, S., Simon, F., Arrese, M., Cabrera, D., Elorza, A., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.3390/ijms21217922
• SARS-COV-2/RENIN-ANGIOTENSIN SYSTEM Autores: Gonzalez, A., Orozco-Aguilar, J., Achiardi, O., Simon, F., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.3390/ijms21217904
• ROLE OF OXIDATIVE STRESS IN HEPATIC AND EXTRAHEPATIC DYSFUNCTIONS DURING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) Autores: Gonzalez, A., Huerta-Salgado, C., Orozco-Aguilar, J., Aguirre, F., Tacchi, F., Simon, F., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.1155/2020/1617805
• ANGIOTENSIN-(1-7) PREVENTS LIPOPOLYSACCHARIDE-INDUCED AUTOPHAGY VIA THE MAS RECEPTOR IN SKELETAL MUSCLE Autores: Rivera, C., Abrigo, J., Tacchi, F., Simon, F., Brandan, E., Santos, A., Bader, M., Chiong, M., Cabello-Verrugio, C., Año: 2020 Link: https://doi.org/10.3390/ijms21249344
• IMPACT OF EXERCISE TRAINING ON THE SARCOPENIA CRITERIA IN NON-ALCOHOLIC FATTY LIVER DISEASE Autores: Gonzalez, A., Valero-Breton, M., Huerta-Salgado, C., Achiardi, O., Simon, F., Cabello-Verrugio, C., Año: 2021 Link: https://doi.org/10.4081/ejtm.2021.9630
• COBALT IONS INDUCE METABOLIC STRESS IN SYNOVIAL FIBROBLASTS AND SECRETION OF CYTOKINES/CHEMOKINES THAT MAY BE DIAGNOSTIC MARKERS FOR ADVERSE LOCAL TISSUE REACTIONS TO HIP IMPLANTS Autores: Eltit, F., Noble, J., Sharma, M., Benam, N., Haegert, A., Bell, H., Simon, F., Duncan, P., Garbuz, S., Greidanus, V., Masri, A., Ng, L., Wang, R., Cox, E., Año: 2021 Link: https://doi.org/10.1016/j.actbio.2021.06.039
• REDOX-DEPENDENT EFFECTS IN THE PHYSIOPATHOLOGICAL ROLE OF BILE ACIDS Autores: Orozco-Aguilar, J., Simon, F., Cabello-Verrugio, C., Año: 2021 Link: https://doi.org/10.1155/2021/4847941
• THE CRITICAL ROLE OF OXIDATIVE STRESS IN SARCOPENIC OBESITY Autores: Gonzalez, A., Simon, F., Achiardi, O., Vilos, C., Cabrera, D., Cabello-Verrugio, C., Año: 2021 Link: https://doi.org/10.1155/2021/4493817
• SCAFFOLD BIOMATERIALS AND NANO-BASED THERAPEUTIC STRATEGIES FOR SKELETAL MUSCLE REGENERATION Autores: Tacchi, F., Orozco-Aguilar, J., Gutiérrez, D., Simon, F., Salazar, J., Vilos, C., Cabello-Verrugio, C., Año: 2021 Link: https://doi.org/10.2217/nnm-2021-0224
• COMBINED ADMINISTRATION OF ANDROGRAPHOLIDE AND ANGIOTENSIN- (1-7) SYNERGICALLY INCREASES THE MUSCLE FUNCTION AND STRENGTH IN AGED MICE Autores: Johanna Abrigo;Felipe Simon;Daniel Cabrera;Cristian Vilos;Claudio Cabello-Verrugio; Año: 2022 Link: https://doi.org/10.2174/1566524021666211207112106
• BILE ACIDS INDUCE ALTERATIONS IN MITOCHONDRIAL FUNCTION IN SKELETAL MUSCLE FIBERS Autores: Johanna Abrigo;Hugo Olguín;Danae Gutierrez;Franco Tacchi;Marco Arrese;Daniel Cabrera;Mayalen Valero-Breton;Alvaro A. Elorza;Felipe Simon;Claudio Cabello-Verrugio; Año: 2022 Link: https://doi.org/10.3390/antiox11091706
• IMPACT OF EXERCISE TRAINING ON THE SARCOPENIA CRITERIA IN NON-ALCOHOLIC FATTY LIVER DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS Autores: Gonzalez, A.;Valero-Breton, M.;Huerta-Salgado, C.;Achiardi, O.;Simon, F.;Cabello-Verrugio, C.; Año: 2021 Link: https://doi.org/10.4081/ejtm.2021.9630
• CORRECTION: OXHDL CONTROLS LOX-1 EXPRESSION AND PLASMA MEMBRANE LOCALIZATION THROUGH A MECHANISM DEPENDENT ON NOX/ROS/NF-B PATHWAY ON ENDOTHELIAL CELLS (LABORATORY INVESTIGATION (2019) 99 3 (421-437) 10.1038/S41374-018-0151-3) Autores: Pérez, L.;Vallejos, A.;Echeverria, C.;Varela, D.;Cabello-Verrugio, C.;Simon, F.; Año: 2020 Link: https://doi.org/10.1038/s41374-020-0375-x
• SARS-COV-2/RENIN-ANGIOTENSIN SYSTEM: DECIPHERING THE CLUES FOR A COUPLE WITH POTENTIALLY HARMFUL EFFECTS ON SKELETAL MUSCLE Autores: Gonzalez, A.;Orozco-Aguilar, J.;Achiardi, O.;Simon, F.;Cabello-Verrugio, C.; Año: 2020 Link: https://doi.org/10.3390/ijms21217904
• EFFECT OF DIETARY SUPPLEMENTS WITH -3 FATTY ACIDS ASCORBIC ACID AND POLYPHENOLIC ANTIOXIDANT FLAVONOID ON GENE EXPRESSION ORGAN FAILURE AND MORTALITY IN ENDOTOXEMIA-INDUCED SEPTIC RATS Autores: Yolanda Prado;Cesar Echeverría;Carmen G. Feijóo;Claudia A. Riedel;Claudio Cabello-Verrugio;Juan F. Santibanez;Felipe Simon; Año: 2023 Link: https://doi.org/10.3390/antiox12030659
• SEPSIS-INDUCED COAGULOPATHY PHENOTYPE INDUCED BY OXIDIZED HIGH-DENSITY LIPOPROTEIN ASSOCIATED WITH INCREASED MORTALITY IN SEPTIC-SHOCK PATIENTS Autores: Yolanda Prado;Pablo Tapia;Felipe Eltit;Cristian Reyes-Martínez;Carmen G. Feijóo;Felipe M. Llancalahuen;Claudia A. Riedel;Claudio Cabello-Verrugio;Jimmy Stehberg;Felipe Simon; Año: 2023 Link: https://doi.org/10.3390/antiox12030543
• OXIDIZED HIGH-DENSITY LIPOPROTEIN INDUCES ENDOTHELIAL FIBROSIS PROMOTING HYPERPERMEABILITY HYPOTENSION AND INCREASED MORTALITY Autores: Macarena Rojas;Yolanda Prado;Pablo Tapia;Leandro J. Carreño;Claudio Cabello-Verrugio;Felipe Simon; Año: 2022 Link: https://doi.org/10.3390/antiox11122469