Alvaro Cerda Maureira

Líneas de investigación

• Applied Molecular Biology for diagnostic and prognosis of metabolic diseases
• Genetic and epigenetic determinants of obesity
• Infectobesity
• Pharmacogenomics

Proyectos adjudicados

• COVID-19 Y SU IMPACTO EN SALUD CARDIOVASCULAR: EFECTOS A CORTO Y MEDIANO PLAZO DE LA INFECCIÓN POR SARS-COV-2 SOBRE EL RIESGO CARDIOMETABÓLICO EN POBLACIÓN ADULTA (2021) Fuente: ANID FONIS | Rol:

Tus publicaciones

• PERIPHERAL BLOOD MIROME IDENTIFIED MIR-155 AS POTENTIAL BIOMARKER OF METS AND CARDIOMETABOLIC RISK IN OBESE PATIENTS Año: 2021 Link: https://doi.org/10.3390/ijms22031468
• STATINS DIFFERENTIALLY MODULATE MICRORNAS EXPRESSION IN PERIPHERAL CELLS OF HYPERLIPIDEMIC SUBJECTS: A PILOT STUDY Año: 2020 Link: https://doi.org/10.1016/j.ejps.2018.02.007
• HIGH PREVALENCE OF OVERWEIGHT OBESITY INSULIN RESISTANCE AND METABOLIC SYNDROME IN RURAL CHILDREN AND ADOLESCENTSALTA PREVALENCIA DE TRASTORNOS NUTRICIONALES POR EXCESO RESISTENCIA INSULÍNICA Y SÍNDROME METABÓLICO EN ESCOLARES DE LA COMUNA DE CARAHUE REGIÓN DE LA ARAUCANÍA Año: 2020 Link: https://doi.org/10.4067/s0034-98872018000900978
• INFLUENCE OF PCSK9 POLYMORPHISMS ON PLASMA LIPIDS AND RESPONSE TO ATORVASTATIN TREATMENT IN BRAZILIAN SUBJECTS Año: 2020 Link: https://doi.org/10.1016/j.jacl.2014.02.008
• ALTERED MICRORNOME PROFILING IN STATIN-INDUCED HEPG2 CELLS: A PILOT STUDY IDENTIFYING POTENTIAL NEW BIOMARKERS INVOLVED IN LIPID-LOWERING TREATMENT Año: 2020 Link: https://doi.org/10.1007/s10557-015-6627-0
• INCREASED CLOPIDOGREL RESPONSE IS ASSOCIATED WITH ABCC3 EXPRESSION: A PILOT STUDY Año: 2020 Link: https://doi.org/10.1016/j.cca.2011.10.018
• MALDI-TOF MS AND 16S RNA IDENTIFICATION OF CULTURABLE GASTRIC MICROBIOTA: VARIABILITY ASSOCIATED WITH THE PRESENCE OF HELICOBACTER PYLORI Año: 2020 Link: https://doi.org/10.3390/microorganisms8111763
• LEPTIN RECEPTOR GENE POLYMORPHISMS ARE ASSOCIATED WITH ADIPOSITY AND METABOLIC ALTERATIONS IN BRAZILIAN INDIVIDUALSPOLIMORFSMOS NO GENE DO RECEPTOR DE LEPTINA SO ASSOCIADOS COM ADIPOSIDADE E ALTERAES METABÓLICAS EM INDIVÍDUOS BRASILEIROS Año: 2020
• INFLUENCE OF THE CYP3A4/5 GENETIC SCORE AND ABCB1 POLYMORPHISMS ON TACROLIMUS EXPOSURE AND RENAL FUNCTION IN BRAZILIAN KIDNEY TRANSPLANT PATIENTS Año: 2020 Link: https://doi.org/10.1097/FPC.0000000000000237
• EFFECTS OF CLOPIDOGREL ON INFLAMMATORY CYTOKINES AND ADHESION MOLECULES IN HUMAN ENDOTHELIAL CELLS: ROLE OF NITRIC OXIDE MEDIATING PLEIOTROPIC EFFECTS Año: 2020 Link: https://doi.org/10.1111/1755-5922.12261
• POLYMORPHISMS IN GENES INVOLVED IN THE LEPTIN-MELANOCORTIN PATHWAY ARE ASSOCIATED WITH OBESITY-RELATED CARDIOMETABOLIC ALTERATIONS IN A SOUTHERN CHILEAN POPULATION Año: 2020 Link: https://doi.org/10.1007/s40291-017-0306-8
• INFLUENCE OF POLYMORPHISMS AND CHOLESTEROL-LOWERING TREATMENT ON SCARB1 MRNA EXPRESSION Año: 2020 Link: https://doi.org/10.5551/jat.6544
• ATORVASTATIN AND HORMONE THERAPY INFLUENCE EXPRESSION OF ABCA1 APOA1 AND SCARB1 IN MONONUCLEAR CELLS FROM HYPERCHOLESTEROLEMIC POSTMENOPAUSAL WOMEN Año: 2020 Link: https://doi.org/10.1016/j.jsbmb.2013.08.017
• PHARMACOGENETICS OF DRUG METABOLIZING ENZYMES IN BRAZILIAN POPULATIONS Año: 2020 Link: https://doi.org/10.1515/dmdi-2013-0067
• MODULATION OF ADHESION MOLECULES BY CHOLESTEROL-LOWERING THERAPY IN MONONUCLEAR CELLS FROM HYPERCHOLESTEROLEMIC PATIENTS Año: 2020 Link: https://doi.org/10.1111/1755-5922.12126
• POLYMORPHISMS IN ANTITHROMBIN AND IN TISSUE FACTOR PATHWAY INHIBITOR GENES ARE ASSOCIATED WITH RECURRENT PREGNANCY LOSS Año: 2020 Link: https://doi.org/10.1160/TH12-03-0177
• LACK OF ASSOCIATION OF ESTROGEN RECEPTOR ALPHA GENE POLYMORPHISMS WITH CARDIORESPIRATORY AND METABOLIC VARIABLES IN YOUNG WOMEN Año: 2020 Link: https://doi.org/10.3390/ijms131013691
• ATORVASTATIN AND HORMONE THERAPY EFFECTS ON APOE MRNA EXPRESSION IN HYPERCHOLESTEROLEMIC POSTMENOPAUSAL WOMEN Año: 2020 Link: https://doi.org/10.1016/j.jsbmb.2011.11.001
• INFLUENCE OF SCARB1 POLYMORPHISMS ON SERUM LIPIDS OF HYPERCHOLESTEROLEMIC INDIVIDUALS TREATED WITH ATORVASTATIN Año: 2020 Link: https://doi.org/10.1016/j.cca.2010.01.002
• ADENOVIRUS 36 SEROPOSITIVITY IS RELATED TO OBESITY RISK GLYCEMIC CONTROL AND LEPTIN LEVELS IN CHILEAN SUBJECTS Año: 2020 Link: https://doi.org/10.1038/s41366-019-0321-4
• CYP3A53 AND CYP2C83 VARIANTS INFLUENCE EXPOSURE AND CLINICAL OUTCOMES OF TACROLIMUS-BASED THERAPY Año: 2020 Link: https://doi.org/10.2217/pgs-2019-0120
• HIGH PREVALENCE OF DYSLIPIDEMIA AND HIGH ATHEROGENIC INDEX OF PLASMA IN CHILDREN AND ADOLESCENTSALTA PREVALENCIA DE DISLIPIDEMIAS Y RIESGO ATEROGÉNICO EN UNA POBLACIÓN INFANTO-JUVENIL Año: 2020 Link: https://doi.org/10.4067/S0034-98872018001001112
• PHARMACOGENETIC IMPLICATIONS IN THE MANAGEMENT OF METABOLIC DISEASES IN BRAZILIAN POPULATIONS Año: 2020 Link: https://doi.org/10.1590/s2175-97902018000001005
• POLYMORPHISMS IN MTOR AND CALCINEURIN SIGNALING PATHWAYS ARE ASSOCIATED WITH LONG-TERM CLINICAL OUTCOMES IN KIDNEY TRANSPLANT RECIPIENTS Año: 2020 Link: https://doi.org/10.3389/fphar.2018.01296
• EFFECTS OF SHORT-TERM ADD-ON EZETIMIBE TO STATIN TREATMENT ON EXPRESSION OF ADIPOKINES AND INFLAMMATORY MARKERS IN DIABETIC AND DYSLIPIDEMIC PATIENTS Año: 2020 Link: https://doi.org/10.1111/1755-5922.12307
• MOLECULAR MECHANISMS OF MEMBRANE IMPERMEABILITY IN CLINICAL ISOLATES OF ENTEROBACTERIACEAE EXPOSED TO IMIPENEM SELECTIVE PRESSURE Año: 2020 Link: https://doi.org/10.1016/j.ijantimicag.2016.04.016
• ASSOCIATION OF ESTROGEN RECEPTOR ALPHA GENE POLYMORPHISMS WITH AUTONOMIC MODULATION OF HEART RATE IN USERS AND NONUSERS OF ORAL CONTRACEPTIVES Año: 2020 Link: https://doi.org/10.1016/j.contraception.2012.11.001
• EFFECTS OF ATORVASTATIN ON CYP3A4 AND CYP3A5 MRNA EXPRESSION IN MONONUCLEAR CELLS AND CYP3A ACTIVITY IN HYPERCHOLERESTEROLEMIC PATIENTS Año: 2020 Link: https://doi.org/10.1016/j.cca.2013.03.007
• MOLECULAR MECHANISMS UNDERLYING STATIN EFFECTS ON GENES INVOLVED IN THE REVERSE CHOLESTEROL TRANSPORT Año: 2020 Link: https://doi.org/10.1515/dmdi-2012-0007
• ABCA1 AND ABCG1 EXPRESSIONS ARE REGULATED BY STATINS AND EZETIMIBE IN CACO-2 CELLS Año: 2020 Link: https://doi.org/10.1515/DMDI.2011.101
• ADIPOQ AND IL6 VARIANTS ARE ASSOCIATED WITH A PRO-INFLAMMATORY STATUS IN OBESES WITH CARDIOMETABOLIC DYSFUNCTION Año: 2020 Link: https://doi.org/10.1186/s13098-015-0027-2
• IMPACT OF 3UTR GENETIC VARIANTS IN PCSK9 AND LDLR GENES ON PLASMA LIPID TRAITS AND RESPONSE TO ATORVASTATIN IN BRAZILIAN SUBJECTS: A PILOT STUDY Año: 2020
• ROLE OF MICRORNAS 221/222 ON STATIN INDUCED NITRIC OXIDE RELEASE IN HUMAN ENDOTHELIAL CELLS Año: 2020 Link: https://doi.org/10.5935/abc.20140192
• GENETIC SCORING TO PREDICT ANTIHYPERTENSIVE DRUG RESPONSE USING GENE VARIANTS ASSOCIATED WITH HYPERTENSION Año: 2020 Link: https://doi.org/10.2217/pgs.13.179
• RELATIONSHIP OF NAT2 CYP2E1 AND GSTM1/GSTT1 POLYMORPHISMS WITH MILD ELEVATION OF LIVER ENZYMES IN BRAZILIAN INDIVIDUALS UNDER ANTI-TUBERCULOSIS DRUG THERAPY Año: 2020 Link: https://doi.org/10.1016/j.cca.2012.10.030
• DIFFERENTIATION OF AFRICAN COMPONENTS OF ANCESTRY TO STRATIFY GROUPS IN A CASE-CONTROL STUDY OF A BRAZILIAN URBAN POPULATION Año: 2020 Link: https://doi.org/10.1089/gtmb.2011.0267
• APOLIPOPROTEIN E MRNA EXPRESSION IN MONONUCLEAR CELLS FROM NORMOLIPIDEMIC AND HYPERCHOLESTEROLEMIC INDIVIDUALS TREATED WITH ATORVASTATIN Año: 2020 Link: https://doi.org/10.1186/1476-511X-10-206
• EFFECTS OF LIPID-LOWERING DRUGS ON REVERSE CHOLESTEROL TRANSPORT GENE EXPRESSIONS IN PERIPHERAL BLOOD MONONUCLEAR AND HEPG2 CELLS Año: 2020 Link: https://doi.org/10.2217/pgs.10.93
• NO ASSOCIATION BETWEEN COMMON GLY972ARG VARIANT OF THE INSULIN RECEPTOR SUBSTRATE-1 AND POLYCYSTIC OVARY SYNDROME IN SOUTHERN CHILEAN WOMEN Año: 2020 Link: https://doi.org/10.1016/j.cca.2007.12.018
• DIFFERENTIALLY EXPRESSED URINARY EXO-MIRS AND CLINICAL OUTCOMES IN KIDNEY RECIPIENTS ON SHORT-TERM TACROLIMUS THERAPY: A PILOT STUDY Autores: Costa de Freitas, Renata Caroline; Bortolin, Raul Hernandes; Vecchia Genvigir, Fabiana Dalla; Bonezi, Vivian; Crespo Hirata, Thiago Dominguez; Felipe, Claudia Rosso; Tedesco-Silva, Helio, Jr.; Medina-Pestana, Jose Osmar; Cerda, Alvaro; Doi, Sonia Quateli; Hirata, Mario Hiroyuki; Crespo Hirata, Rosario Dominguez Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=639326
• INFLUENCE OF ADENOVIRUS 36 SEROPOSITIVITY ON THE EXPRESSION OF ADIPOGENIC MICRORNAS IN OBESE SUBJECTS Autores: Manriquez, Victor; Gutierrez, Alvaro; Morales, Alexis; Brito, Roberto; Pavez, Monica; Sapunar, Jorge; Fonseca, Luis; Molina, Victor; Ortiz, Eugenia; Barra, Maria Ines; Reimer, Camila; Charles, Maria; Schneider, Constance; Cerda, Alvaro Año: 2020 Link: https://investigadores.anid.cl//en/public_search/work?id=639322
• MALDI-TOF MS AND 16S RNA IDENTIFICATION OF CULTURABLE GASTRIC MICROBIOTA: VARIABILITY ASSOCIATED WITH THE PRESENCE OF HELICOBACTER PYLORI Autores: Troncoso, Claudia; Pavez, Monica; Cerda, Alvaro; Oporto, Marcelo; Villarroel, Daniel; Hofmann, Edmundo; Rios, Eddy; Sierralta, Armando; Copelli, Luis; Barrientos, Leticia Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=639325
• CHARACTERIZATION OF THE ADIPOGENIC PROTEIN E4ORF1 FROM ADENOVIRUS 36 THROUGH AN IN SILICO APPROACH Autores: Gutierrez, Alvaro; Ferreira, Glaucio Monteiro; Machuca, Juan; Venthur, Herbert; Feres, Fausto; Hirata, Mario Hirouyki; Hirata, Rosario Dominguez Crespo; Cerda, Alvaro Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=639323
• DIFFERENTIAL EXPRESSION OF GENES RELATED TO CALCINEURIN AND MTOR SIGNALING AND REGULATORY MIRNAS IN PERIPHERAL BLOOD FROM KIDNEY RECIPIENTS UNDER TACROLIMUS-BASED THERAPY Autores: Bonezi, Vivian; Genvigir, Fabiana Dalla Vecchia; Salgado, Patricia de Cassia; Felipe, Claudia Rosso; Tedesco-Silva Jr, Helio; Medina-Pestana, Jose Osmar; Cerda, Alvaro; Doi, Sonia Quateli; Hirata, Mario Hiroyuki; Crespo Hirata, Rosario Dominguez Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=639324
• POLYPHARMACY IS ASSOCIATED WITH FRAILTY, NUTRITIONAL RISK AND CHRONIC DISEASE IN CHILEAN OLDER ADULTS: REMARKS FROM PIEI-ES STUDY Autores: Arauna, Diego; Cerda, Alvaro; Garcia, Jose Francisco; Wehinger, Sergio; Castro, Felipe; Mendez, Diego; Alarcon, Marcelo; Fuentes, Eduardo; Palomo, Ivan Año: 2020 Link: https://investigadores.anid.cl//es/public_search/work?id=617174
• ASSOCIATION OF PROGRANULIN GENE EXPRESSION FROM DYSPEPTIC PATIENTS WITH VIRULENT HELICOBACTER PYLORI STRAINS; IN VIVO MODEL Autores: Claudia Troncoso Muñoz;Mónica Pavez;Alvaro Cerda;Victor Manríquez;Aurora Prado;Edmundo Hofmann;Eddy Ríos;Armando Sierralta;Luis Copelli;Leticia Barrientos; Año: 2022 Link: https://doi.org/10.3390/microorganisms10050998
• GENETIC VARIANT ABCC1 RS45511401 IS ASSOCIATED WITH INCREASED RESPONSE TO STATINS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA Autores: Carolina Dagli Hernandez;Jéssica B. Borges;Elisangela da Silva Rodrigues Maral;Renata Caroline Costa de Freitas;Augusto Akira Mori;Rodrigo Marques Gonalves;Andre Arpad Faludi;Victor Fernandes de Oliveira;Glaucio Monteiro Ferreira;Gisele Medeiros Bastos;Yitian Zhou;Volker M Lauschke;Alvaro Cerda;Hirata MH;Rosario Dominguez Crespo Hirata; Año: 2022 Link: https://doi.org/10.3390/pharmaceutics14050944
• REDRAWING CITIES WITH CHILDREN AND ADOLESCENTS: DEVELOPMENT OF A FRAMEWORK AND OPPORTUNITY INDEX FOR WELLBEINGTHE REDIBUJA STUDY PROTOCOL Autores: Nicolas Aguilar-Farias;Maria Francisca Roman Mella;Andrea Cortinez-ORyan;Jaime Carcamo-Oyarzun;Alvaro Cerda;Marcelo Toledo-Vargas;Sebastian Miranda-Marquez;Susana Cortes-Morales;Teresa Balboa-Castillo; Año: 2022 Link: https://doi.org/10.3390/ijerph19095312
• EFFECT OF STATINS ON LIPID METABOLISM-RELATED MICRORNA EXPRESSION IN HEPG2 CELLS Autores: Cerda, Alvaro;Bortolin, Raul Hernandes;Manriquez, Victor;Salazar, Luis;Zambrano, Tomas;Fajardo, Cristina Moreno;Hirata, Mario Hiroyuki;Hirata, Rosario Dominguez Crespo; Año: 2021 Link: https://doi.org/10.1007/S43440-021-00241-3
• GENOMICS EPIGENOMICS AND PHARMACOGENOMICS OF FAMILIAL HYPERCHOLESTEROLEMIA (FHBGEP): A STUDY PROTOCOL Autores: Borges, Jessica Bassani;de Oliveira, Victor Fernandes;Ferreira, Glaucio Monteiro;Los, Bruna;Almendros Afonso Barbosa, Thais Kristini;Rodrigues Marcal, Elisangela da Silva;Dagli-Hernandez, Carolina;Costa de Freitas, Renata Caroline;Bortolin, Raul Hernandes;Mori, Augusto Akira;Crespo Hirata, Thiago Dominguez;Imoto Nakaya, Helder Takashi;Bastos, Gisele Medeiros;Thurow, Helena Strelow;Goncalves, Rodrigo Marques;de Araujo, Daniel Branco;Zatz, Henry Paulo;Bertolami, Adriana;Faludi, Andre Arpad;Bertolami, Marcelo Chiara;de Moraes Rego Sousa, Amanda Guerra;Franca, Joao Italo Dias;Jannes, Cinthia Elim;Pereira, Alexandre da Costa;Nakazone, Marcelo Arruda;Silva Souza, Doroteia Rossi;Carmo, Tayanne Silva;Sampaio, Marcelo Ferraz;Gorjao, Renata;Pithon-Curi, Tania Cristina;Moriel, Patricia;Silbiger, Vivian Nogueira;Luchessi, Andre Ducati;Goes de Araujo, Jessica Nayara;Naslavsky, Michel Satya;Wang, Jaqueline Yu Ting;Kronenberger, Thales;Cerda, Alvaro;Lin-Wang, Hui Tzu;Garofalo, Adriana Regina;Fajardo, Cristina Moreno;Crespo Hirata, Rosario Dominguez;Hirata, Mario Hiroyuki; Año: 2021 Link: https://doi.org/10.1016/J.SAPHARM.2020.10.007
• HIGH SERUM MIR-421 IS ASSOCIATED WITH METABOLIC DYSREGULATION AND INFLAMMATION IN PATIENTS WITH METABOLIC SYNDROME Autores: Braga, Aecio A.;Bortolin, Raul H.;Graciano-Saldarriaga, Magda E.;Hirata, Thiago D. C.;Cerda, Alvaro;de Freitas, Renata C. C.;Lin-Wang, Hui T.;Borges, Jessica B.;Franca, Joao I. D.;Masi, Laureane N.;Curi, Rui;Pithon-Curi, Tania C.;Sampaio, Marcelo F.;Castro, Lara R.;Bastos, Gisele M.;Hirata, Rosario D. C.;Hirata, Mario H.; Año: 2021 Link: https://doi.org/10.2217/EPI-2020-0247