Waldo Andrés Acevedo Castillo

Líneas de investigación

• Bioquímica Farmacológica
• Química de Alimentos
• Bioinformática Estructural

Proyectos adjudicados

• DOCTORAL FELLOWSHIP, 2013, National Council for Scientific Research(Santiago;RM;CL)
• EVALUATING MODIFIED AMINO ACIDS WITH POTENTIAL INHIBITORY ACTIVITY OF HUMAN BITTER TASTE RECEPTORS ACTIVATED BY STEVIOL GLYCOSIDES THROUGH CELL-BASED FUNCTIONAL ASSAYS, 2022, Pontificia Universidad Catlica de Valparaso
• EVALUACIN DE EXTRACTOS PURIFICADOS DE CRCUMA LONGA Y MICROSORUN SCOLOPENDRIA SOBRE LA DISBIOSIS DEL MICROBIOMA PROVOCADO POR PATGENOS OPORTUNISTAS EN UN MODELO DE PIEL USANDO SCAFFOLDS, 2021, Pontificia Universidad Catlica de Valparaso
• STRUCTURE-BASED VIRTUAL SCREENING FOR IDENTIFICATION OF AMINO ACID DERIVATIVES AS POTENTIAL BLOCKERS OF HUMAN BITTER TASTE RECEPTORS ACTIVATED BY STEVIOL GLYCOSIDES, 2020, Pontificia Universidad Catlica de Valparaso
• IMPROVING ACCURACY IN THE TIMING OF SMOLT TRANSFER AND THEIR PERFORMANCE IN SEAWATER: A COMPARATIVE STUDY OF SEVERAL MOLECULAR MARKERS EXPRESSED IN GILLS OF ATLANTIC SALMON THROUGH REAL-TIME PCR, 2018, CONICYT
• CARACTERIZACIN ESTRUCTURAL Y ENERGTICA DE LA INTERACCIN ENTRE PPTIDOS ANLOGOS A SMAC/DIABLO Y SURVIVINA UTILIZANDO HERRAMIENTAS BIOINFORMTICAS, 2012, Pontificia Universidad Catlica de Valparaso
• TECNOLOGAS DE LA SALUD EN SALMONICULTURA=> DESARROLLO DE FORMULACIONES CON PPTIDOS ACTIVOS PARA DISMINUIR EL ESTRS SISTMICO, 2011-2011, Innova-Chile (11IDL2-10586)
• SIMULACIN COMPUTACIONAL DE MOLCULAS NANOMATERIALES Y SISTEMAS BIOLGICOS DE INTERS EXPERIMENTAL A TRAVS DE ANLISIS DE ESTADO DE EXCITACIN EN SEMICONDUCTORES, 2010-2010, Proyecto Anillo (ACT/24/2006)
• DOCTORAL FELLOWSHIP, 2013, National Council for Scientific Research(Santiago;RM;CL)
• EVALUATING MODIFIED AMINO ACIDS WITH POTENTIAL INHIBITORY ACTIVITY OF HUMAN BITTER TASTE RECEPTORS ACTIVATED BY STEVIOL GLYCOSIDES THROUGH CELL-BASED FUNCTIONAL ASSAYS, 2022, Pontificia Universidad Catolica de Valparaiso
• EVALUACION DE EXTRACTOS PURIFICADOS DE CURCUMA LONGA Y MICROSORUN SCOLOPENDRIA SOBRE LA DISBIOSIS DEL MICROBIOMA PROVOCADO POR PATOGENOS OPORTUNISTAS EN UN MODELO DE PIEL USANDO SCAFFOLDS, 2021, Pontificia Universidad Catolica de Valparaiso
• STRUCTURE-BASED VIRTUAL SCREENING FOR IDENTIFICATION OF AMINO ACID DERIVATIVES AS POTENTIAL BLOCKERS OF HUMAN BITTER TASTE RECEPTORS ACTIVATED BY STEVIOL GLYCOSIDES, 2020, Pontificia Universidad Catolica de Valparaiso
• IMPROVING ACCURACY IN THE TIMING OF SMOLT TRANSFER AND THEIR PERFORMANCE IN SEAWATER: A COMPARATIVE STUDY OF SEVERAL MOLECULAR MARKERS EXPRESSED IN GILLS OF ATLANTIC SALMON THROUGH REAL-TIME PCR, 2018, CONICYT
• CARACTERIZACION ESTRUCTURAL Y ENERGETICA DE LA INTERACCION ENTRE PEPTIDOS ANALOGOS A SMAC/DIABLO Y SURVIVINA UTILIZANDO HERRAMIENTAS BIOINFORMATICAS, 2012, Pontificia Universidad Catolica de Valparaiso
• TECNOLOGIAS DE LA SALUD EN SALMONICULTURA=> DESARROLLO DE FORMULACIONES CON PEPTIDOS ACTIVOS PARA DISMINUIR EL ESTRES SISTEMICO, 2011-2011, Innova-Chile (11IDL2-10586)
• SIMULACION COMPUTACIONAL DE MOLECULAS NANOMATERIALES Y SISTEMAS BIOLOGICOS DE INTERES EXPERIMENTAL A TRAVES DE ANALISIS DE ESTADO DE EXCITACION EN SEMICONDUCTORES, 2010-2010, Proyecto Anillo (ACT/24/2006)

Tus publicaciones

• SYNTHESIS BIOLOGICAL ACTIVITY AND MOLECULAR MODELLING STUDIES OF NAPHTHOQUINONE DERIVATIVES AS PROMISING ANTICANCER CANDIDATES TARGETING COX2, https://www.mdpi.com/1424-8247/15/5/541, 2022, nan
• SYNTHESIS IN VITRO EVALUATION AND MOLECULAR DOCKING STUDIES OF NOVEL NAPHTHOISOXAZOLEQUINONE CARBOXAMIDE HYBRIDS AS POTENTIAL ANTITUMOR AGENTS, https://www.tandfonline.com/doi/abs/10.1080/10406638.2022.2095410?journalCode=gpol20, 2022, nan
• GENETIC DIVERSITY AND BIOLOGICAL ACTIVITY OF CURCUMA LONGA ECOTYPES FROM RAPA NUI USING MOLECULAR MARKERS, https://doi.org/10.1016/J.SJBS.2020.10.062, 2021, nan
• IN VITRO EVALUATION AND MOLECULAR DOCKING OF QS-21 AND QUILLAIC ACID FROM QUILLAJA SAPONARIA MOLINA AS GASTRIC CANCER AGENTS, https://doi.org/10.1038/S41598-020-67442-3, 2020, nan
• L-MALATE -2 PROTONATION STATE IS REQUIRED FOR EFFICIENT DECARBOXYLATION TOL-LACTATE BY THE MALOLACTIC ENZYME OFOENOCOCCUS OENI, https://doi.org/10.3390/MOLECULES25153431, 2020, nan
• ANTIPROLIFERATIVE BENZOINDAZOLEQUINONES AS POTENTIAL CYCLOOXYGENASE-2 INHIBITORS, https://doi.org/10.3390/molecules24122261, 2019, nan
• THE ORIGIN OF UNPLEASANT AFTERTASTES IN SYNTHETIC SWEETENERS: A HYPOTHESIS, https://doi.org/10.3389/fmolb.2018.00119, 2019, nan
• IDENTIFYING THE INTERACTIONS BETWEEN NATURAL NON-CALORIC SWEETENERS AND THE HUMAN SWEET RECEPTOR BY MOLECULAR DOCKING, https://doi.org/10.1016/j.foodchem.2018.04.113, 2018, nan
• SELECTING OPTIMAL MIXTURES OF NATURAL SWEETENERS FOR CARBONATED SOFT DRINKS THROUGH MULTI-OBJECTIVE DECISION MODELING AND SENSORY VALIDATION, https://doi.org/10.1111/joss.12466, 2018, nan
• DOCKING AND MOLECULAR DYNAMICS OF STEVIOL GLYCOSIDEHUMAN BITTER RECEPTOR INTERACTIONS, https://doi.org/10.1021/acs.jafc.6b02840, 2016, nan
• BINDING OF ARACHIDONIC ACID AND TWO FLAVONOID INHIBITORS TO HUMAN 12- AND 15-LIPOXYGENASES: A STEERED MOLECULAR DYNAMICS STUDY, https://doi.org/10.1007/s00894-009-0616-9, 2009, nan